The Effect of Diabetes Mellitus on the Treatment Outcome of Tuberculosis

Introduction: Tuberculosis and diabetes mellitus both are the two most important public health problems inIndia. India is presently having highest burden of tuberculosis second mellitusglobally. Many studies have shown to poorer treatment outcome in diabetic patients.Aim: To evaluate difference antitubercular regimens patients compared tonon-diabetic patients.Materials Methods: Active presenting Department Respiratory Medicine ofIPGME&R, Kolkata were taken divided into groups- with without (according toADA criteria). Two groups matched for age, sex, addiction habits, history contact andprevious tuberculosis. Treatment been given boththe according standard protocol they followed up glycemic control, fortuberculosis parameters clinicoradiological outcome) including adverse drugreaction, need hospitalization mortality. Statistical analysis was also done accuracy HbA1c atthe end predict outcome.Results: In this analysis, outcome(36%) unsuccessful (10%), higher rate hospitalisation(OR=8.5) mortality (4%). ROCcurve showed a cut-off HbA1c<7.4 good at treatment.Conclusion: Diabetes has negative effect on anti-tubercular as poor control duringthe course often lead So every patient should be screenedfor onset proper anti-diabetic therapy along standardanti-tubercular favourable outcome.